Difference Between Precancerous Lesions and Precancerous Condition of Oral Cavity

Pre-cancerous lesion -



It is Defined as a morphologically altered tissue in which Cancer is more likely to occur, than its apparently moral counter parts.

For example,

1) Leukoplakia -

Leukoplakia white Patches

White Patches

 It is defined as a white patch or plaque in the oral cavity, which cannot be scrappled off or stripped off easily and more over , which cannot be characterized clinically or pathologically as any other disease.

2) Erythroplakia -

Redness in buccal mucosa

Redness in buccal mucosa

It is applied to any area of reddened, velvety texture mucosa that cannot be identified on the basis of clinical and histopathologic examination as being cause by inflammation or any other disease process.

3) Carcinoma in situ -

Combination of Erythroplakia and Leukoplakia

Its also called "Interepithelial carcinoma ".
It is a condition which arises frequently on skin , but occurs also on mucus membrane including those of oral cavity.

4) Actinic keratosis-

It is a cutaneous pre-malignant lesion.
Similarly , Actinic chelitis which is associated with lower lip.


Pre-Cancerous Condition -


It is defined as a genralized state or condition associated with significantly increased risk for cancer development.

For example-

1) Oral Submucous Fibrosis -

OSMF

Bud shaped ovula

 It is aa chronic and high risk precancerous condition. The lesion is characterized by juxta epithelial inflammatory reaction followed by fibroelastic changes of lamina propria with epithelial atrophy leading to stiffness of oral mucosa and causing trismus and inability to eat.


2) Oral lichen planus-

Oral Lichen Planus

Oral Lichen Planus

It is a chronic inflammatory condition that affects mucous membrane inside your mouth. Oral lichen planus may appear as White lesions patches, red, swollen tissues or open sores. These lesions may cause burning pain or other discomfort.





3) Systemic lupus erythematosus-

Oral lupus erytmatosus

It is characterized by presence of abnormal antibodies and immune system.



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